Brain MRI displayed bilateral T2 hypersignal in the thalamus and other parts of the brain these shown changes cause with speech, walking, and eating and most of time is normally in elderly people and can be fixed with therapy and drugs. In the follow-up, her signs got better in the next MRI. The MRI shown that the lesion got smaller. At the age of 25, her neurological condition calmed down with the help of MRI she had reasonable dystonia and could walk and eat without help. For drugs they gave her based on the MRIs were benzodiazepines and penicillamine were helpful but on the other had speech therapy was withdrawn as it was unproductive. At this time, she tried zolpidem at bedtime for sleeping troubles and reported a different effect of this drug on her voice and this helped with her speech in the end. Finally this young women she would of not got the help she needed if it was not for the use of MRIs.
Poujois, A., Pernon, M., Trocello, J., & Woimant, F. (2017). Dystonic Dysarthria in Wilson Disease: Efficacy of Zolpidem. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671475/
T2-weighted brain MRI shows bilateral and symmetric hyperintensities in the thalamus, and cerebellum In the photos on this website used from the MRIs show how the use of penicillamine. These images are from a to a 22-year aged man with jaw-opening dystonia and he was given penicillamine. After 20 days new brain MRI showed worsening dystonia with the use of Penicillamine which is different then the women beforehand this drug helped her out a lot so this drug was discontinued for him this study showed use of penicillamine in patients with these disease may not work all the time and without MRIs we may not of seen this effect in many patients like him.
15-year-old boy presented with shakes of right hand and speech. Neurologic checkup using MRIs showed Wilson’s disease. The brain MRI showed bilateral T2 hyperintensity involving thalamus, and brainstem. The MRI not only provides chemical information on heavy metal spreading like copper but also shapes, signs and symptoms in Wilson’s disease which sometimes looks like as panda as this paper states.
Singh, P., Ahluwalia, A., Saggar, K., & Grewal, C. S. (2011). Wilson’s disease: MRI features. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173909/