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Urinary Tract Infection or UTI is one of the most common bacterial infection and it is mainly caused by both gram-negative and gram-positive bacteria. The most common agent for both complicated and uncomplicated UTI is Escherichia coli. Diarrheal diseases which is the second leading cause of death in children under five years old are also caused by E. coli. Virulent E. coli strains causes either non-inflammatory diarrhea and inflammatory diarrhea. It transmits through fecal-oral route, the pili allows the bacteria to colonize the mucosa). The Cytotonic enterotoxins induces watery diarrhea, then plasmid-encoded invasion factors permit the invasion of the mucosa inducing damage to the tissues

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